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A comparative account of microRNA resources, feature-validations and application-based categorizations

miTALos

Tool namemiTALos
URL1. http://mips.helmholtz-muenchen.de/mitalos/index.jsp 2. http://hmgu.de/cmb/mitalos
Important featuresWeb based resource on microRNA-directed regulation of signaling pathways in human and mouse developed by the integration of five different microRNA target prediction tools:TargetScan, RNA22, TargetSpy, PITA and PicTar and two different signaling pathway resources (KEGG and NCI: National Cancer Institute Pathway Interaction Database).
CitationsKowarsch A, Preusse M, Marr C, Theis FJ. miTALOS: analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs. RNA. 2011 May;17(5):809-19. Epub 2011 Mar 25. PubMed PMID: 21441347; PubMed Central PMCID: PMC3078731.
Year of publication2011
Rank by usage frequency100
CommentsDownloadable on request
FunctionFUNCTIONAL ANALYSIS: pathways, SPECIES: mouse, SPECIES: miscellaneous, 1. http://mips.helmholtz-muenchen.de/mitalos/index.jsp 2. http://hmgu.de/cmb/mitalos, Web based resource on microRNA-directed regulation of signaling pathways in human and mouse developed by the integration of five different microRNA target prediction tools:TargetScan- RNA22- TargetSpy- PITA and PicTar and two different signaling pathway resources (KEGG and NCI: National Cancer Institute Pathway Interaction Database)., Kowarsch A- Preusse M- Marr C- Theis FJ. miTALOS: analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs. RNA. 2011 May;17(5):809-19. Epub 2011 Mar 25. PubMed PMID: 21441347; PubMed Central PMCID: PMC3078731. , 2011, 100, Downloadable on request, Online, I. SPECIES SUPPORTED INCLUDE: human II. QUERY OR INPUT DATA: 1. Select microRNA or cluster from the given list or enter desired list of microRNAs (one per line) 2. Select type of analysis by choosing either tissue or pathway 3. Set advanced parameters III. OUTPUT DATA: depicts target predictions and their potential regulatory role in specific tissue- signaling pathway(s) or disease condition.
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