mirKO | Tool name | mirKO |
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| URL | http://www.knockoutmouse.org/martsearch |
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| Important features | Mouse microRNA knockout resource is a collection of mutant embryonic stem cells harboring specific deletions for most of the microRNA genes reposited in miRBase. |
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| Citations | Prosser HM, Koike-Yusa H, Cooper JD, Law FC, Bradley A. A resource of vectors
and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug
7;29(9):840-5. doi: 10.1038/nbt.1929. PubMed PMID: 21822254; PubMed Central
PMCID: PMC3242032.
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| Year of publication | 2011 |
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| Rank by usage frequency | 100 |
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| Comments | |
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| Function | EXPERIMENTAL data analysis, SPECIES: mouse, http://www.knockoutmouse.org/martsearch, Mouse microRNA knockout resource is a collection of mutant embryonic stem cells harboring specific deletions for most of the microRNA genes reposited in miRBase., Prosser HM- Koike-Yusa H- Cooper JD- Law FC- Bradley A. A resource of vectors
and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug
7;29(9):840-5. doi: 10.1038/nbt.1929. PubMed PMID: 21822254; PubMed Central
PMCID: PMC3242032.
, 2011, 100, I. SPECIES SUPPORTED INCLUDE: mouse II. QUERY OR INPUT DATA: 1. Search by gene- product identifiers- gene/ marker symbol or name- synonym- MGI accession ID- Ensemble geneID- Vega Gene ID- Entrez gene ID- CCDS ID- OMIM ID- Confirmed Positive Phenotype Test Name or any desired key word.
III. OUTPUT DATA: details on selected gene- IKMC vectors and ES cells- details of ES cell clones (cassette type- deletion alleles)- details of targeting vector (design- cassette- backbone etc)- availability and ordering information. IV. ADDITIONAL INFORMATION: details on mirKO can be obtained from the ES cell repository such as International knockout mouse consortium. |
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