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A comparative account of microRNA resources, feature-validations and application-based categorizations

miRWalk

Tool namemiRWalk
URLhttp://mirwalk.uni-hd.de/
Important featuresDatabase of predicted and validated microRNAs.
CitationsDweep H, Sticht C, Pandey P, Gretz N. miRWalk - Database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform. 2011 May 14. [Epub ahead of print] PubMed PMID: 21605702.
Year of publication2011
Rank by usage frequency94
CommentsThe ARGONAUTE database was incorporated in miRWalk.
FunctionFIND TARGET: database, FUNCTIONAL ANALYSIS: pathways, EXPERIMENTAL: microRNA data with evidence, DISEASE/ TISSUE SPECIFIC, SPECIES: human, SPECIES: rat, SPECIES: miscellaneous, http://mirwalk.uni-hd.de/, Database of predicted and validated microRNAs. , Dweep H- Sticht C- Pandey P- Gretz N. miRWalk - Database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform. 2011 May 14. [Epub ahead of print] PubMed PMID: 21605702. , 2011, 94, The ARGONAUTE database was incorporated in miRWalk., Online, I. SPECIES SUPPORTED INCLUDE: human- mouse- rat II. QUERY OR INPUT DATA: 1. Enter gene list (single or multiple entries) 2. Choose gene region (promoter- 3'UTR- 5' UTR- CDS etc) - 3. Choose from other options such as transcript length- seed region- p value (default values) 4. Choose from among 8 target prediction tools III. OUTPUT DATA: Depending on the type of analysis chosen :1. MiRNA-targets interactions using miRWalk algorithm on the complete sequence (promoter- 5' UTR- CDS and 3' UTR) 3. MiRNA-targets predictions by RNA22- miRanda- miRDB- TargetScan- RNAhybrid- PITA- PICTAR- and Diana-microT 4. Genes involved in human physiological pathways and OMIM disorders 5. Mitochondrial target predictions for human- mouse and rat 6. Proteins that play a role in microRNA processing.
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